- Joined
- Sep 18, 2023
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This reaction works well in water only. What is the purpose of the toluene? Once HCl is added, basify using 50% NaOH solution (contents will urn blueish). You do not need a baking soda wash if done that way. Flood the flask with water and steam distill the P2P. It will be clear/slightly yellow as it distills. Once neon orange color is coming over, its more than done. Use DCM to extract P2P from water, dry and remove with distillation. Apply vacuum and distill pure P2P. Surprisingly this reaction works better at larger scale in the 81-87% yield if things are tweaked. Lower scale you achieve 73-75% (not very good) to 77-78%.
You also do not need 5-6 hours to add Acid.
You also do not need 5-6 hours to add Acid.