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Would you get other esters of ritalinic acid if you'd do the last step in other solvents (IPA = isopropylphenidate, EtOH = ethylphenidate etc.)?
G.Patton
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Would you get other esters of ritalinic acid if you'd do the last step in other solvents (IPA = isopropylphenidate, EtOH = ethylphenidate etc.)?
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Chefy77What do you mean with 4f, i can not follow you?
cokemuffinHi. NaOH in IPA will completely spoil your ritalin*HCl. You can get ritalin freebase by aqueous NaOH and then carry out esterification.
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oh i'm sorry that comment was meant for you. ever make 4f?
G.Patton
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Could you also do it with a ritalinic acid ester? I'd assume that as an example you could just hydrolyse methylphenidate HCl with NaOH in ipa to get the sodium salt of ritalinic acid, then just add hydrochloric acid to the solution to get isopropylphenidate HCl, saturate the solution with NaCl to push the IPH out of the water and let the solution form two layers, than decant the top layer and let the IPH crystallize from it (let the solvent evaporate). But that's just an assumption, so would that work?