P2P synthesis from BMK glycidate ethers

[Saul]

this is the preparation of P2P Phenylacetone CAS 103-79-7 made use of BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with main ingredient sulfonic acid strength is 75% CAS 7664-38-2
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we are going to prepare 1 kg of BMK
take a 5 liter double neck flask
add 500ml boiling water . start with the mixer.
now slowly add 1kg of BMK salt. then add 1 liter of sulfonic acid. now connect the reflux and heat the contents of the flask to max temperature. plus minus 130°c. use a powerful mixer
Let it boil in reflux for 4 hours.
take the top layer and pour it into a measuring cup.
let the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

now boil 1 liter of water and add it to the measuring cup. use a hand mixer to mix everything.
After mixing for a few minutes, let the measuring cup cool to room temperature.
remove the top white layer (this is water and waste that we don't need)
the bottom layer is P2P purified and ready to use.

ps: in this preparation we don't have to worry about water remaining in our P2P because water weighs less than P2P

ps2: if you keep these ratios, the P2P will have a ph value of 4 .
if you use more sulfonic acid the ph value will drop to 1. Therefore it is not necessary to use too much sulfonic acid.

 

[w2x3f5]

this is the preparation of P2P Phenylacetone CAS 103-79-7 made use of BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with main ingredient sulfonic acid strength is 75% CAS 7664-38-2
-------------------------------------------------- ------------------------------
we are going to prepare 1 kg of BMK
take a 5 liter double neck flask
add 500ml boiling water . start with the mixer.
now slowly add 1kg of BMK salt. then add 1 liter of sulfonic acid. now connect the reflux and heat the contents of the flask to max temperature. plus minus 130°c. use a powerful mixer
Let it boil in reflux for 4 hours.
take the top layer and pour it into a measuring cup.
let the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

now boil 1 liter of water and add it to the measuring cup. use a hand mixer to mix everything.
After mixing for a few minutes, let the measuring cup cool to room temperature.
remove the top white layer (this is water and waste that we don't need)
the bottom layer is P2P purified and ready to use.

ps: in this preparation we don't have to worry about water remaining in our P2P because water weighs less than P2P

ps2: if you keep these ratios, the P2P will have a ph value of 4 .
if you use more sulfonic acid the ph value will drop to 1. Therefore it is not necessary to use too much sulfonic acid.

T0RI tried your version of the synthesis, but did not use water, the synthesis takes place in microwave irradiation. At a certain moment, the temperature dropped sharply from 110 degrees to 50 degrees, the reaction was still violent. Have you noticed a drop in temperature as carbon dioxide emission starts?

 

[cernalit0000]

I tried your version of the synthesis, but did not use water, the synthesis takes place in microwave irradiation. At a certain moment, the temperature dropped sharply from 110 degrees to 50 degrees, the reaction was still violent. Have you noticed a drop in temperature as carbon dioxide emission starts? View attachment 9888

w2x3f5buenas noches una pregunta de 1k bmk 5449-12-7. Relise con 1k fosforico. Baje al ph 3 purificado.
al final rindios. 200g polvo es normal o en q falle??

 

[w2x3f5]

buenas noches una pregunta de 1k bmk 5449-12-7. Relise con 1k fosforico. Baje al ph 3 purificado.
al final rindios. 200g polvo es normal o en q falle??

cernalit0000Puedes escribirme en inglés en mensajes privados

 

[G.Patton]

edit // VERY slowly in a liter of 80°c phosphoric acid (NO WATER)

SaulDo you use H3PO4 cons or diluted solution? Thank you for your feedback.

 

[cernalit0000]

Do you use H3PO4 cons or diluted solution? Thank you for your feedback.

G.PattonBuenas noches realiza la síntesis
Utilice 1k bmk 5449-12-7
2 litros de agua. 200g de sosa
Ajite 1 hora que disolviera 70g agrege 1k fosforico. Durante 2 horas mas
800g p2p. Despues purifique con agua. Me dio los 750 ml
Reaccione. Solto 500 ml para destilar. Y en la destiladora
Me dio 200 mil para amarrar con tartaricoo. Poco rendimiento final. 100g en q falleee????

 

[G.Patton]

Buenas noches realiza la síntesis
Utilice 1k bmk 5449-12-7
2 litros de agua. 200g de sosa
Ajite 1 hora que disolviera 70g agrege 1k fosforico. Durante 2 horas mas
800g p2p. Despues purifique con agua. Me dio los 750 ml
Reaccione. Solto 500 ml para destilar. Y en la destiladora
Me dio 200 mil para amarrar con tartaricoo. Poco rendimiento final. 100g en q falleee????

cernalit0000Hola, amigo. English please.

 

[w2x3f5]

Try hydrolysis in pure phosphoric acid in the microwave. I got a yield of 80% percent of the theoretical, p2p of good quality, the meth turned out to be excellent, now I am optimizing the synthesis of p2p on sodium borohydride.
Later I will publish the result of repeated synthesis in the microwave, it is important to obtain a stable repeating synthesis result.

 

[mithyl2]

Try hydrolysis in pure phosphoric acid in the microwave. I got a yield of 80% percent of the theoretical, p2p of good quality, the meth turned out to be excellent, now I am optimizing the synthesis of p2p on sodium borohydride.
Later I will publish the result of repeated synthesis in the microwave, it is important to obtain a stable repeating synthesis result.

w2x3f5thanks for letting us know. what's the best way to get pure phosphoric acid? it's a solid isn't it?

 

[Win Win]

Introduction​

Hydrolysis of BMK glycidate ethers is represented in this topic. The procedure is the same for ethyl (Et) [cas 41232-97-7] and methyl (Me) [cas 80532-66-7] esters of glycidic acid. In case of sodium (Na) salt of this acid [cas 5449-12-7], you can skip first stage of NaOH addition and start from acid hydrolysis. In addition, purification method of obtained P2P is described. This procedure have to be committed to get pure Phenylacetone (P2P) for further syntheses of methamphetamine or amphetamine.

Suppliers of BMK glycidate ethers can be found in BB Listing.

Difficulty rating: 2/10 View attachment 6617 ​

Equipment and glassware:

• 1000 mL Round bottom flask;
• Reflux condenser;
• Retort stand and clamp for securing apparatus;
• pH indicator paper;
• Vacuum source (optional);
• Rotovap machine (optional);
• Glass rod and spatula;
• 100 mL x2; 250 mL x2; 500 mL x2 Beakers;
• Magnetic or top stirrer with a heating plate;
• Water bath;
• Funel;
• 1000 mL Separatory funnel;
• Vacuum distillation setup (optional);

Reagents:​

• 100 g BMK glycidate ethers (cas 80532-66-7; cas 41232-97-7; cas 5449-12-7);
• ~20 g NaOH or KOH;
• ~80 ml HCl (35%) or 100 ml H2SO4 (45%);
• ~600 mL DCM or Petroleum Ether;
• ~100 g MgSO4 or Na2SO4;
• ~500-600 mL Distilled water;
• ~ 50 g NaCl (optional);

View attachment 6616 ​

Hydrolysis of BMK glycidates​

1. NaOH (or KOH) 20g is dissolved in 250-300 ml distilled water with stirring. The reaction mixture (Rm) have to be cooled to room temperature. BMK glycidate 100 g (methyl or ethyl ester) is added and dissolved completely. Part of BMK is hydrolyzed during this procedure and floated as an oil in the surface of Rm. Rm is stired for 1 h at 75-80 °C with a reflux condenser.
2. Then, 200 ml HCl (35%) or 240 ml H2SO4 (45%) are added in small portions to Rm and heated to 80-90 °C and stired for 3 h. Rm have to be cooled to room temperature, the precipitate is filtered.
3. The reaction solution is extracted with DCM or petroleum ether 3 x 100 ml. Extract is washed with brine to neutral pH 7 several times. Extract is dried with MgSO4 (or Na2SO4) (optional) and filtered from solids.
4. An organic solvent (DCM or petroleum ether) is distilled off to give 65 ml of P2P.
​

Phenylacetone (P2P) synthesis via BMK ethyl glycidate​

Download Video

Phenylacetone (P2P) Synthesis Via BMK Ethyl Glycidate

• Novator
• Jun 1, 2023
• 53
• 1-phenyl-2-propanone benzaldehyde bmk bmk ethyl glycidate bmk glycidic meth p2p synthesis

1) BMK ethyl glycidate synthesis from benzaldehyde.
2) BMK glycidic acid (sodium salt) synthesis...

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P2P purification​

1. The resulting phenylacetone (P2P) is transferred to a round bottom flask with distilled water 1:1 (w/w) and distilled with steam under vacuum.
2. Purified P2P from receiver flask is extracted from water mixture with DCM (or petroleuum ether) 3 x 100 mL. Extract is dried with MgSO4 (or Na2SO4).
3. The resulting solution is filtered from the solids (drying agent) and then an organic solvent is distilled off.​

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Steam P2P Distillation as a Purification Method

• G.Patton
• Aug 12, 2023
• 23
• 1-phenyl-2-propanone cas 103-79-7 p2p p2p purification phenylacetone steam distillation

Steam P2P Distillation as a Purification Method...

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Phenylacetone can be stored long time in a sealed vessel in a freezer. It is recommended to distill it before further syntheses of methamphetamine or amphetamine. Avoid direct sunlight onto phenylacetone and exposure to high temperatures.​

G.PattonI want to ask if this recipe works.

 

[G.Patton]

I want to ask if this recipe works.

Win WinHello, I don't know. You didn't describe your way clearly. I can't answer you. I can't read your mind, man. You can write me in DM with your issue in order to avoid flood under this topic,

 

[chef learner]

If I use BMK to make P2P, what method should I use to make methamphetamine in the second stage?

 

[Johnson212]

If I have bmk sodium salt, should I start directly at the HCL hydrolysis step?

 

[Throw-off]

If I have bmk sodium salt, should I start directly at the HCL hydrolysis step?

Johnson212Yes. READ the whole thread it was answered 7 times previously.