P2P synthesis from BMK glycidate ethers

[Saul]

this is the preparation of P2P Phenylacetone CAS 103-79-7 made use of BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with main ingredient sulfonic acid strength is 75% CAS 7664-38-2
-------------------------------------------------- ------------------------------
we are going to prepare 1 kg of BMK
take a 5 liter double neck flask
add 500ml boiling water . start with the mixer.
now slowly add 1kg of BMK salt. then add 1 liter of sulfonic acid. now connect the reflux and heat the contents of the flask to max temperature. plus minus 130°c. use a powerful mixer
Let it boil in reflux for 4 hours.
take the top layer and pour it into a measuring cup.
let the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

now boil 1 liter of water and add it to the measuring cup. use a hand mixer to mix everything.
After mixing for a few minutes, let the measuring cup cool to room temperature.
remove the top white layer (this is water and waste that we don't need)
the bottom layer is P2P purified and ready to use.

ps: in this preparation we don't have to worry about water remaining in our P2P because water weighs less than P2P

ps2: if you keep these ratios, the P2P will have a ph value of 4 .
if you use more sulfonic acid the ph value will drop to 1. Therefore it is not necessary to use too much sulfonic acid.

 

[Win Win]

this is the preparation of P2P Phenylacetone CAS 103-79-7 made use of BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with main ingredient sulfonic acid strength is 75% CAS 7664-38-2
-------------------------------------------------- ------------------------------
we are going to prepare 1 kg of BMK
take a 5 liter double neck flask
add 500ml boiling water . start with the mixer.
now slowly add 1kg of BMK salt. then add 1 liter of sulfonic acid. now connect the reflux and heat the contents of the flask to max temperature. plus minus 130°c. use a powerful mixer
Let it boil in reflux for 4 hours.
take the top layer and pour it into a measuring cup.
let the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

now boil 1 liter of water and add it to the measuring cup. use a hand mixer to mix everything.
After mixing for a few minutes, let the measuring cup cool to room temperature.
remove the top white layer (this is water and waste that we don't need)
the bottom layer is P2P purified and ready to use.

ps: in this preparation we don't have to worry about water remaining in our P2P because water weighs less than P2P

ps2: if you keep these ratios, the P2P will have a ph value of 4 .
if you use more sulfonic acid the ph value will drop to 1. Therefore it is not necessary to use too much sulfonic acid.

T0RHi sir… after reaction so i still need extracted by DCM and vaporrator?

 

[damakemi]

this is the preparation of P2P Phenylacetone CAS 103-79-7 made use of BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with main ingredient sulfonic acid strength is 75% CAS 7664-38-2
-------------------------------------------------- ------------------------------
we are going to prepare 1 kg of BMK
take a 5 liter double neck flask
add 500ml boiling water . start with the mixer.
now slowly add 1kg of BMK salt. then add 1 liter of sulfonic acid. now connect the reflux and heat the contents of the flask to max temperature. plus minus 130°c. use a powerful mixer
Let it boil in reflux for 4 hours.
take the top layer and pour it into a measuring cup.
let the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

now boil 1 liter of water and add it to the measuring cup. use a hand mixer to mix everything.
After mixing for a few minutes, let the measuring cup cool to room temperature.
remove the top white layer (this is water and waste that we don't need)
the bottom layer is P2P purified and ready to use.

ps: in this preparation we don't have to worry about water remaining in our P2P because water weighs less than P2P

ps2: if you keep these ratios, the P2P will have a ph value of 4 .
if you use more sulfonic acid the ph value will drop to 1. Therefore it is not necessary to use too much sulfonic acid.

T0Rlet the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

what are the method on the second run using the bottom layer from the previous time?

 

[Win Win]

this is the preparation of P2P Phenylacetone CAS 103-79-7 made use of BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with main ingredient sulfonic acid strength is 75% CAS 7664-38-2
-------------------------------------------------- ------------------------------
we are going to prepare 1 kg of BMK
take a 5 liter double neck flask
add 500ml boiling water . start with the mixer.
now slowly add 1kg of BMK salt. then add 1 liter of sulfonic acid. now connect the reflux and heat the contents of the flask to max temperature. plus minus 130°c. use a powerful mixer
Let it boil in reflux for 4 hours.
take the top layer and pour it into a measuring cup.
let the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

now boil 1 liter of water and add it to the measuring cup. use a hand mixer to mix everything.
After mixing for a few minutes, let the measuring cup cool to room temperature.
remove the top white layer (this is water and waste that we don't need)
the bottom layer is P2P purified and ready to use.

ps: in this preparation we don't have to worry about water remaining in our P2P because water weighs less than P2P

ps2: if you keep these ratios, the P2P will have a ph value of 4 .
if you use more sulfonic acid the ph value will drop to 1. Therefore it is not necessary to use too much sulfonic acid.

SaulHi sir. I am facing a difficult problem now, my p2p has turned milky white. Is there any way to save it? Can I use distilled water for washing?

 

[jessejames122669]

I got confused over the sulfonic acid part. I understand he was using phosphoric acid.
I now have sulfonic acid. Not phosphoric. Can sulfonic be used?
Anybody try it? Results?

 

[Jesse_Pinkman_]

I got confused over the sulfonic acid part. I understand he was using phosphoric acid.
I now have sulfonic acid. Not phosphoric. Can sulfonic be used?
Anybody try it? Results?

jessejames122669All 3 acids (hci/phos/sulf) work, but there seems to different results in yield and different experiences. Every one has its one temp and time to convert and maybe prufication necessary.

 

[Win Win]

After reaction is it must extracted by dcm? And wash with brine?

 

[Saul]

@Win Win no you dont need dcm for this

 

[Saul]

@jessejames122669 yes son phosphoric acid I use very sorry, but we can change mistakes after 10 minutes
Very frustrating, I know .

 

[rothschild33]

After acquiring possible P2P from this reaction, would bisulfite adduct confirm that it is in fact P2P? or are there other ketones that could possibly result from the procedure?

 

[MisterAnonymous]

I used phosphoric acid and first the Rm went from light green to dark green after boiling for 3 hours 2 layers formed and i took the top layer but it's a very thick solution very tick is this P2P or something else?

 

[Saul]

I used phosphoric acid and first the Rm went from light green to dark green after boiling for 3 hours 2 layers formed and i took the top layer but it's a very thick solution very tick is this P2P or something else? View attachment 25872

MisterAnonymouslooking verry good .
have you wash it with hot water ?

 

[MisterAnonymous]

looking verry good .
have you wash it with hot water ?

T0RNo is it normal that it's so thick when i store it in the fridge it doesn't come out the bottle?

 

[Saul]

No is it normal that it's so thick when i store it in the fridge it doesn't come out the bottle?

MisterAnonymousyou need to wash it use mixer with hot water at least 3 liters and then give it 12hours

 

[Win Win]

Introduction​

Hydrolysis of BMK glycidate ethers is represented in this topic. The procedure is the same for ethyl (Et) [cas 41232-97-7] and methyl (Me) [cas 80532-66-7] esters of glycidic acid. In case of sodium (Na) salt of this acid [cas 5449-12-7], you can skip first stage of NaOH addition and start from acid hydrolysis. In addition, purification method of obtained P2P is described. This procedure have to be committed to get pure Phenylacetone (P2P) for further syntheses of methamphetamine or amphetamine.

Suppliers of BMK glycidate ethers can be found in BB Listing.

Difficulty rating: 2/10 View attachment 6617 ​

Equipment and glassware:

• 1000 mL Round bottom flask;
• Reflux condenser;
• Retort stand and clamp for securing apparatus;
• pH indicator paper;
• Vacuum source (optional);
• Rotovap machine (optional);
• Glass rod and spatula;
• 100 mL x2; 250 mL x2; 500 mL x2 Beakers;
• Magnetic or top stirrer with a heating plate;
• Water bath;
• Funel;
• 1000 mL Separatory funnel;
• Vacuum distillation setup (optional);

Reagents:​

• 100 g BMK glycidate ethers (cas 80532-66-7; cas 41232-97-7; cas 5449-12-7);
• ~20 g NaOH or KOH;
• ~80 ml HCl (35%) or 100 ml H2SO4 (45%);
• ~600 mL DCM or Petroleum Ether;
• ~100 g MgSO4 or Na2SO4;
• ~500-600 mL Distilled water;
• ~ 50 g NaCl (optional);

View attachment 6616 ​

Hydrolysis of BMK glycidates​

1. NaOH (or KOH) 20g is dissolved in 250-300 ml distilled water with stirring. The reaction mixture (Rm) have to be cooled to room temperature. BMK glycidate 100 g (methyl or ethyl ester) is added and dissolved completely. Part of BMK is hydrolyzed during this procedure and floated as an oil in the surface of Rm. Rm is stired for 1 h at 75-80 °C with a reflux condenser.
2. Then, 200 ml HCl (35%) or 240 ml H2SO4 (45%) are added in small portions to Rm and heated to 80-90 °C and stired for 3 h. Rm have to be cooled to room temperature, the precipitate is filtered.
3. The reaction solution is extracted with DCM or petroleum ether 3 x 100 ml. Extract is washed with brine to neutral pH 7 several times. Extract is dried with MgSO4 (or Na2SO4) (optional) and filtered from solids.
4. An organic solvent (DCM or petroleum ether) is distilled off to give 65 ml of P2P.
​

Phenylacetone (P2P) synthesis via BMK ethyl glycidate​

Download Video

Phenylacetone (P2P) Synthesis Via BMK Ethyl Glycidate

• Novator
• Jun 1, 2023
• 53
• 1-phenyl-2-propanone benzaldehyde bmk bmk ethyl glycidate bmk glycidic meth p2p synthesis

1) BMK ethyl glycidate synthesis from benzaldehyde.
2) BMK glycidic acid (sodium salt) synthesis...

​

P2P purification​

1. The resulting phenylacetone (P2P) is transferred to a round bottom flask with distilled water 1:1 (w/w) and distilled with steam under vacuum.
2. Purified P2P from receiver flask is extracted from water mixture with DCM (or petroleuum ether) 3 x 100 mL. Extract is dried with MgSO4 (or Na2SO4).
3. The resulting solution is filtered from the solids (drying agent) and then an organic solvent is distilled off.​

Download Video

Steam P2P Distillation as a Purification Method

• G.Patton
• Aug 12, 2023
• 23
• 1-phenyl-2-propanone cas 103-79-7 p2p p2p purification phenylacetone steam distillation

Steam P2P Distillation as a Purification Method...

​

Phenylacetone can be stored long time in a sealed vessel in a freezer. It is recommended to distill it before further syntheses of methamphetamine or amphetamine. Avoid direct sunlight onto phenylacetone and exposure to high temperatures.​

G.PattonHi sir. I am facing a difficult problem now, my p2p has turned milky white. Is there any way to save it? Can I use distilled water for washing?

 

[G.Patton]

Hi sir. I am facing a difficult problem now, my p2p has turned milky white. Is there any way to save it? Can I use distilled water for washing?

Win WinI don't know why it happened with your p2p. How do you store it? In an opened bottle under sun light? You can steam distill it, it should help to save part of this.

 

[Win Win]

I don't know why it happened with your p2p. How do you store it? In an opened bottle under sun light? You can steam distill it, it should help to save part of this.

G.PattonI don't know why this happened, I sealed it and stored it in a cool place. Do I need to add distilled water for distillation? At what degree is the temperature controlled?

 

[G.Patton]

I don't know why this happened, I sealed it and stored it in a cool place. Do I need to add distilled water for distillation? At what degree is the temperature controlled?

Win WinWatch video about d-meth manufacturing, there is video tutorial how to carry out steam distillation of P2P.

 

[Win Win]

Watch video about d-meth manufacturing, there is video tutorial how to carry out steam distillation of P2P.

G.PattonNoted with thanks

 

[btcboss2022]

Introduction​

Hydrolysis of BMK glycidate ethers is represented in this topic. The procedure is the same for ethyl (Et) [cas 41232-97-7] and methyl (Me) [cas 80532-66-7] esters of glycidic acid. In case of sodium (Na) salt of this acid [cas 5449-12-7], you can skip first stage of NaOH addition and start from acid hydrolysis. In addition, purification method of obtained P2P is described. This procedure have to be committed to get pure Phenylacetone (P2P) for further syntheses of methamphetamine or amphetamine.

Suppliers of BMK glycidate ethers can be found in BB Listing.

Difficulty rating: 2/10 View attachment 6617 ​

Equipment and glassware:

• 1000 mL Round bottom flask;
• Reflux condenser;
• Retort stand and clamp for securing apparatus;
• pH indicator paper;
• Vacuum source (optional);
• Rotovap machine (optional);
• Glass rod and spatula;
• 100 mL x2; 250 mL x2; 500 mL x2 Beakers;
• Magnetic or top stirrer with a heating plate;
• Water bath;
• Funel;
• 1000 mL Separatory funnel;
• Vacuum distillation setup (optional);

Reagents:​

• 100 g BMK glycidate ethers (cas 80532-66-7; cas 41232-97-7; cas 5449-12-7);
• ~20 g NaOH or KOH;
• ~80 ml HCl (35%) or 100 ml H2SO4 (45%);
• ~600 mL DCM or Petroleum Ether;
• ~100 g MgSO4 or Na2SO4;
• ~500-600 mL Distilled water;
• ~ 50 g NaCl (optional);

View attachment 6616 ​

Hydrolysis of BMK glycidates​

1. NaOH (or KOH) 20g is dissolved in 250-300 ml distilled water with stirring. The reaction mixture (Rm) have to be cooled to room temperature. BMK glycidate 100 g (methyl or ethyl ester) is added and dissolved completely. Part of BMK is hydrolyzed during this procedure and floated as an oil in the surface of Rm. Rm is stired for 1 h at 75-80 °C with a reflux condenser.
2. Then, 200 ml HCl (35%) or 240 ml H2SO4 (45%) are added in small portions to Rm and heated to 80-90 °C and stired for 3 h. Rm have to be cooled to room temperature, the precipitate is filtered.
3. The reaction solution is extracted with DCM or petroleum ether 3 x 100 ml. Extract is washed with brine to neutral pH 7 several times. Extract is dried with MgSO4 (or Na2SO4) (optional) and filtered from solids.
4. An organic solvent (DCM or petroleum ether) is distilled off to give 65 ml of P2P.
​

Phenylacetone (P2P) synthesis via BMK ethyl glycidate​

Download Video

Phenylacetone (P2P) Synthesis Via BMK Ethyl Glycidate

• Novator
• Jun 1, 2023
• 53
• 1-phenyl-2-propanone benzaldehyde bmk bmk ethyl glycidate bmk glycidic meth p2p synthesis

1) BMK ethyl glycidate synthesis from benzaldehyde.
2) BMK glycidic acid (sodium salt) synthesis...

​

P2P purification​

1. The resulting phenylacetone (P2P) is transferred to a round bottom flask with distilled water 1:1 (w/w) and distilled with steam under vacuum.
2. Purified P2P from receiver flask is extracted from water mixture with DCM (or petroleuum ether) 3 x 100 mL. Extract is dried with MgSO4 (or Na2SO4).
3. The resulting solution is filtered from the solids (drying agent) and then an organic solvent is distilled off.​

Download Video

Steam P2P Distillation as a Purification Method

• G.Patton
• Aug 12, 2023
• 23
• 1-phenyl-2-propanone cas 103-79-7 p2p p2p purification phenylacetone steam distillation

Steam P2P Distillation as a Purification Method...

​

Phenylacetone can be stored long time in a sealed vessel in a freezer. It is recommended to distill it before further syntheses of methamphetamine or amphetamine. Avoid direct sunlight onto phenylacetone and exposure to high temperatures.​

G.PattonIs there any way to recover an "overcooked" bmk 5449? I didnt realize about that flask while doing other tasks , I tried the standard and logical ways without success.
Thanks.

 

[G.Patton]

Is there any way to recover an "overcooked" bmk 5449? I didnt realize about that flask while doing other tasks , I tried the standard and logical ways without success.
Thanks.

btcboss2022Hi, I don't clearly understand your issue. Write me DM your problem, I'll try to help you.

 

[Win Win]

I

Introduction​

Hydrolysis of BMK glycidate ethers is represented in this topic. The procedure is the same for ethyl (Et) [cas 41232-97-7] and methyl (Me) [cas 80532-66-7] esters of glycidic acid. In case of sodium (Na) salt of this acid [cas 5449-12-7], you can skip first stage of NaOH addition and start from acid hydrolysis. In addition, purification method of obtained P2P is described. This procedure have to be committed to get pure Phenylacetone (P2P) for further syntheses of methamphetamine or amphetamine.

Suppliers of BMK glycidate ethers can be found in BB Listing.

Difficulty rating: 2/10 View attachment 6617 ​

Equipment and glassware:

• 1000 mL Round bottom flask;
• Reflux condenser;
• Retort stand and clamp for securing apparatus;
• pH indicator paper;
• Vacuum source (optional);
• Rotovap machine (optional);
• Glass rod and spatula;
• 100 mL x2; 250 mL x2; 500 mL x2 Beakers;
• Magnetic or top stirrer with a heating plate;
• Water bath;
• Funel;
• 1000 mL Separatory funnel;
• Vacuum distillation setup (optional);

Reagents:​

• 100 g BMK glycidate ethers (cas 80532-66-7; cas 41232-97-7; cas 5449-12-7);
• ~20 g NaOH or KOH;
• ~80 ml HCl (35%) or 100 ml H2SO4 (45%);
• ~600 mL DCM or Petroleum Ether;
• ~100 g MgSO4 or Na2SO4;
• ~500-600 mL Distilled water;
• ~ 50 g NaCl (optional);

View attachment 6616 ​

Hydrolysis of BMK glycidates​

1. NaOH (or KOH) 20g is dissolved in 250-300 ml distilled water with stirring. The reaction mixture (Rm) have to be cooled to room temperature. BMK glycidate 100 g (methyl or ethyl ester) is added and dissolved completely. Part of BMK is hydrolyzed during this procedure and floated as an oil in the surface of Rm. Rm is stired for 1 h at 75-80 °C with a reflux condenser.
2. Then, 200 ml HCl (35%) or 240 ml H2SO4 (45%) are added in small portions to Rm and heated to 80-90 °C and stired for 3 h. Rm have to be cooled to room temperature, the precipitate is filtered.
3. The reaction solution is extracted with DCM or petroleum ether 3 x 100 ml. Extract is washed with brine to neutral pH 7 several times. Extract is dried with MgSO4 (or Na2SO4) (optional) and filtered from solids.
4. An organic solvent (DCM or petroleum ether) is distilled off to give 65 ml of P2P.
​

Phenylacetone (P2P) synthesis via BMK ethyl glycidate​

Download Video

Phenylacetone (P2P) Synthesis Via BMK Ethyl Glycidate

• Novator
• Jun 1, 2023
• 53
• 1-phenyl-2-propanone benzaldehyde bmk bmk ethyl glycidate bmk glycidic meth p2p synthesis

1) BMK ethyl glycidate synthesis from benzaldehyde.
2) BMK glycidic acid (sodium salt) synthesis...

​

P2P purification​

1. The resulting phenylacetone (P2P) is transferred to a round bottom flask with distilled water 1:1 (w/w) and distilled with steam under vacuum.
2. Purified P2P from receiver flask is extracted from water mixture with DCM (or petroleuum ether) 3 x 100 mL. Extract is dried with MgSO4 (or Na2SO4).
3. The resulting solution is filtered from the solids (drying agent) and then an organic solvent is distilled off.​

Download Video

Steam P2P Distillation as a Purification Method

• G.Patton
• Aug 12, 2023
• 23
• 1-phenyl-2-propanone cas 103-79-7 p2p p2p purification phenylacetone steam distillation

Steam P2P Distillation as a Purification Method...

​

Phenylacetone can be stored long time in a sealed vessel in a freezer. It is recommended to distill it before further syntheses of methamphetamine or amphetamine. Avoid direct sunlight onto phenylacetone and exposure to high temperatures.​

G.PattonI use the method is 100g bmk add 100g distrilled water and 100g HCI after that heat up to 80c reflux 3 hour. Is it ok?